Search Thermo Fisher Scientific
ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release. Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells. Induces apoptosis in cell culture. Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A
100 µL
100 µg
100 µL